特別提示:包括重組人前列腺素D2合成酶(PTGDS)在內(nèi),本公司的所有產(chǎn)品僅可用于科研實驗,嚴(yán)禁用于臨床醫(yī)療及其他非科研用途!
產(chǎn)品名稱:重組人前列腺素D2合成酶(PTGDS)
英文名稱:Recombinant Human Prostaglandin-D2 Synthase
產(chǎn)品貨號:JN0671
產(chǎn)品規(guī)格:10μg|50μg|500μg|1mg
本品由我們的哺乳動物細(xì)胞表達(dá)系統(tǒng)制備而成,目的基因編碼的Ala23-Gln190在C端含有His標(biāo)簽。
PTGDS質(zhì)量控制:>95%(還原性SDS-PAGE)
PTGDS制劑:液體
PTGDS保存:收到貨后請置于-20℃,可保存6個月,避免反復(fù)凍融。
關(guān)于PTGDS:
Prostaglandin-H2 D-Isomerase (PTGDS) belo
ngs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the co
nversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system.
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關(guān)注
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