特別提示:包括重組人LMAN2L(VIP36樣蛋白)在內(nèi),本公司的所有產(chǎn)品僅可用于科研實驗,嚴(yán)禁用于臨床醫(yī)療及其他非科研用途!
產(chǎn)品名稱:重組人LMAN2L(VIP36樣蛋白)
英文名稱:Recombinant Human VIP36-like protein
產(chǎn)品貨號:JN1273
產(chǎn)品規(guī)格:10μg|50μg|500μg|1mg
本品由我們的哺乳動物細(xì)胞表達(dá)系統(tǒng)制備而成,目的基因編碼的Ser19-Ala313在C端含有His標(biāo)簽。
LMAN2L質(zhì)量控制:>95%(還原性SDS-PAGE)
LMAN2L制劑:凍干品
LMAN2L保存:
凍干蛋白置于-20℃以下可長期保存,室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天,可分裝后置于-20℃保存三個月。
LMAN2L復(fù)溶:
打開試劑管前請先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請溶于ddH2O。
復(fù)溶后,請根據(jù)用量分裝凍存,避免反復(fù)凍融。
關(guān)于LMAN2L:
VIP36-like protein (LMAN2L) is a single-pass type I membrane protein and co
ntains 1 L-type lectin-like domain. It is highly expressed in skeletal muscle and kidney, and its intermediate ex
pression levels in heart, liver and placenta, low levels in brain, thymus, spleen, small intestine and lung. LMAN2L may be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. It also may function as a regulator of ERGIC-53.
根據(jù)您的關(guān)注的
重組人LMAN2L(VIP36樣蛋白),VIP36樣蛋白,重組人LMAN2L,重組人VIP36-like protein,重組LMAN2L,重組VIP36-like protein,重組人VIP36樣蛋白,重組VIP36樣蛋白,rLMAN2L,rhLMAN2L,重組人LMAN2L(VIP36樣蛋白),Recombinant Human VIP36-like protein,JN1273,百奧萊博,,,您可能還對以下產(chǎn)品有需求:
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關(guān)注
重組人LMAN2L(VIP36樣蛋白),VIP36樣蛋白,重組人LMAN2L,重組人VIP36-like protein,重組LMAN2L,重組VIP36-like protein,重組人VIP36樣蛋白,重組VIP36樣蛋白,rLMAN2L,rhLMAN2L,重組人LMAN2L(VIP36樣蛋白),Recombinant Human VIP36-like protein,JN1273,百奧萊博,,的同時,為您推薦更多您可能感興趣的產(chǎn)品:
名稱:重組人白介素IL-20(白細(xì)胞介素20)
貨號:JN0356
規(guī)格:10μg|50μg|500μg|1mg
本品由我們的大腸桿菌表達(dá)系統(tǒng)制備,目的基因編碼的Leu25-Glu176表達(dá)純化而來。
IL-20質(zhì)量控制:>95%(還原性SDS-PAGE)。
IL-20制劑:凍干品
IL-20保存:
凍干蛋白可在-20℃長期保存,室溫也可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天。
復(fù)溶后建議分裝凍存在-20℃,可保存3個月,應(yīng)避免反復(fù)凍融。
IL-20復(fù)溶:
1、試劑開蓋前請先離心。
2、復(fù)溶濃度應(yīng)大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復(fù)溶后根據(jù)使用量分裝保存,避免反復(fù)凍融。
關(guān)于IL-20:
Interleukin-20 (IL-20) is a member of the IL-10 family of regulatory cytokines that includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 exhibits approximately 28% amino acid identity with IL-10 and 76% amino acid identity with mouse IL-20. There are two heterodimeric receptor complexes for IL-20. The first is composed of IL-20 Rα and IL-20 Rβ. The second is composed of IL-22 R and IL-20 Rβ. Wher
eas the IL-22 R/IL-20 Rβ complex is shared with IL-24, the IL-20 Rα/IL-20 Rβ complex is shared with both IL-19 and IL-24. IL-20 has been shown to initiate transduction cascades involving STAT3 and stimulates the induction of pro-inflammatory genes including TNF-α and MCP-1. Initial functio
nal studies using transgenic mice suggest that IL-20 has the ability to regulate skin development. The over-ex
pression of both human and mouse forms of IL-20 results in keratinocyte hyper-proliferation, abnormal epidermal differentiation, and neo
natal lethality. In humans, IL-20 and its receptors are up-regulated in psoriatic skin, and polymorphisms in the IL-20 gene have been associated with plaque-type psoriasis. IL-20 may also have a role in hematopoiesis. It enhances the proliferation of multi-potential progenitors in vitro and increases their numbers and cell cycling status in IL-20 transgenic mice. IL-20 is also shown to suppress COX-2 and PGE2 and acts as an inhibitor of angiogenesis in model systems.
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