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產(chǎn)品名稱:重組小鼠聚集素(Clusterin)
英文名稱:Recombinant Mouse Clusterin
產(chǎn)品貨號:JN0973
產(chǎn)品規(guī)格:10μg|50μg|500μg|1mg
本品由我們的哺乳動物細胞表達系統(tǒng)制備而成,目的基因編碼的Glu22-Glu448在C端含有His標(biāo)簽。
Clusterin/CLU質(zhì)量控制:>95%(還原性SDS-PAGE)
Clusterin/CLU制劑:凍干品
Clusterin/CLU保存:
凍干蛋白置于-20℃以下可長期保存,室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天,可分裝后置于-20℃保存三個月。
Clusterin/CLU復(fù)溶:
打開試劑管前請先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請溶于ddH2O。
復(fù)溶后,請根據(jù)用量分裝凍存,避免反復(fù)凍融。
關(guān)于Clusterin/CLU:
Clusterin(CLU) is a secreted protein which belo
ngs to the clusterin family. Itis also a 75 - 80 kDa disulfide-l
inked heterodimeric protein associated with the clearance of cellular debris and apoptosis. Clusterin is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimers disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. It is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amo
ngst others.
根據(jù)您的關(guān)注的
重組小鼠聚集素(Clusterin),重組聚集素,rClusterin,Recombinant Mouse Clusterin,重組Clusterin,重組小鼠聚集素(Clusterin),rmClusterin,重組小鼠Clusterin,重組小鼠聚集素,Clusterin,JN0973,百奧萊博,,,您可能還對以下產(chǎn)品有需求:
名稱:重組人白介素IL-6(白細胞介素6)
貨號:JN0334
規(guī)格:10μg|50μg|500μg|1mg
本品由我們的大腸桿菌表達系統(tǒng)制備,目的基因編碼的Pro29-Met212表達純化而來。
IL-6質(zhì)量控制:>95%(還原性SDS-PAGE)。
IL-6制劑:凍干品
IL-6保存:
凍干蛋白可在-20℃長期保存,室溫也可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天。
復(fù)溶后建議分裝凍存在-20℃,可保存3個月,應(yīng)避免反復(fù)凍融。
IL-6復(fù)溶:
1、試劑開蓋前請先離心。
2、復(fù)溶濃度應(yīng)大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復(fù)溶后根據(jù)使用量分裝保存,避免反復(fù)凍融。
關(guān)于IL-6:
Cytokines of the IL6/GCSF/MGF family are glycoproteins of a
bout 170 to 180 amino acid residues that co
ntain four co
nserved cysteine residues involved in two disulfide bonds. They have a compact, globular fold (similar to other interleukins), stabilized by the 2 disulfide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist; the helices are anti-parallel, with 2 overhand connections, which fall into a 2-stranded anti-parallel beta-sheet. The fourth alpha helix is im
portant to the biological activity of the molecule. Interleukin-6 (IL-6) is an im
portant proinflammatory and immunoregulatory cytokine expressed by various cells. Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.
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關(guān)注
重組小鼠聚集素(Clusterin),重組聚集素,rClusterin,Recombinant Mouse Clusterin,重組Clusterin,重組小鼠聚集素(Clusterin),rmClusterin,重組小鼠Clusterin,重組小鼠聚集素,Clusterin,JN0973,百奧萊博,,的同時,為您推薦更多您可能感興趣的產(chǎn)品:
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