特別提示:包括重組人骨保護素(TNFRSF11B)在內(nèi),本公司的所有產(chǎn)品僅可用于科研實驗,嚴(yán)禁用于臨床醫(yī)療及其他非科研用途!
產(chǎn)品名稱:重組人骨保護素(TNFRSF11B)
英文名稱:Recombinant Human Osteoprotegerin
產(chǎn)品貨號:JN0444
產(chǎn)品規(guī)格:10μg|50μg|500μg|1mg
本品由我們的哺乳動物細胞表達系統(tǒng)制備而成,目的基因編碼的Glu22-Leu401在C端含有His標(biāo)簽。
TNFRSF11B質(zhì)量控制:>95%(還原性SDS-PAGE)
TNFRSF11B制劑:凍干品
TNFRSF11B保存:
凍干蛋白置于-20℃以下可長期保存,室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天,可分裝后置于-20℃保存三個月。
TNFRSF11B復(fù)溶:
打開試劑管前請先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請溶于ddH2O。
復(fù)溶后,請根據(jù)用量分裝凍存,避免反復(fù)凍融。
關(guān)于TNFRSF11B:
TNFRSF11B is a secreted protein, co
ntaining 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting trans
cription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNFRSF11B can reduce the production of osteoclasts by inhibiting the differentiation of osteoclast precursors (osteoclasts are related to monocytes/macrophages and are derived from granulocyte/macrophage-forming co
lony units (CFU-GM)) into osteoclasts and also regulates the resorption of osteoclasts in vitroand in vivo. TNFRSF11B binding to RANKL on osteoblast/stromal cells, blocks the RANKL-RANK ligand interaction between osteoblast/stromal cells and osteoclast precursors. This has the effect of inhibiting the differentiation of the osteoclast precursor into a mature osteoclast.
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重組人骨保護素(TNFRSF11B),重組人TNFRSF11B,重組人骨保護素,TNFRSF11B,Recombinant Human Osteoprotegerin,重組骨保護素,rOsteoprotegerin,重組TNFRSF11B,重組人Osteoprotegerin,重組Osteoprotegerin,rhOsteoprotegerin,rhTNFRSF11B,重組人骨保護素(TNFRSF11B),rTNFRSF11B,JN0444,百奧萊博,,,您可能還對以下產(chǎn)品有需求:
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關(guān)注
重組人骨保護素(TNFRSF11B),重組人TNFRSF11B,重組人骨保護素,TNFRSF11B,Recombinant Human Osteoprotegerin,重組骨保護素,rOsteoprotegerin,重組TNFRSF11B,重組人Osteoprotegerin,重組Osteoprotegerin,rhOsteoprotegerin,rhTNFRSF11B,重組人骨保護素(TNFRSF11B),rTNFRSF11B,JN0444,百奧萊博,,的同時,為您推薦更多您可能感興趣的產(chǎn)品:
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