兔抗HER2/ErbB2抗體是高品質(zhì)的一抗產(chǎn)品，由北京百奧萊博供應(yīng)，本產(chǎn)品僅用于生物化學研究方面，兔抗HER2/ErbB2抗體是我司眾多優(yōu)質(zhì)一抗之一，質(zhì)量堪比同類進口產(chǎn)品，價格非常優(yōu)惠，目前正熱烈促銷中，恭候您的咨詢訂購。...

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產(chǎn)品名稱：兔抗HER2/ErbB2抗體
英文名稱：HER2/ErbB2 Rabbit Polyclonal Antibody
產(chǎn)品貨號：YT723
產(chǎn)品規(guī)格：50μl

本品為來源于兔的抗HER2/ErbB2的多克隆抗體。
宿主：兔
克隆性：多克隆抗體
用途：WB,ICC, IHC,IF
交叉反應(yīng)性：人
分子量：140KDa
推薦稀釋比例：WB(1:500-1:1000),IF(1:200),IHC(1:200),ICC(1:200)

about this Antibody
Name	HER2/ErbB2 Rabbit Polyclonal Antibody
Category	Polyclonal antibody(pAb); Primary antibody
Isotype	IgG
Purification	Peptide affinity purified
about the Immunogen
Immunogen	This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to human ErbB2.
Gene ID	2064
SwissProt	P04626
Synonyms	CerbB2 antibody; CerbB2/neu protein antibody; ErbB2 antibody; HER2 antibody
Category	RTK
Background	HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or overexpression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approx. 30% of breast cancer patients. Over-expression is also known to occur in ovarian, stomach, and aggressive forms of uterine cancer, such as uterine serous endometrial carcinoma. The expression of HER2 is regulated by signaling through estrogen receptors. Normally, estradiol and tamoxifen acting through the estrogen receptor down-regulate the expression of HER2. However, when the ratio of the coactivator AIB-3 exceeds that of the corepressor PAX2, the expression of HER2 is upregulated in the presence of tamoxifen, leading to tamoxifen-resistant breast cancer.

注意事項：
1. 如果本抗體用于Western blot (WB)、免疫熒光(IF)、免疫細胞化學(ICC)等實驗，請注意回收使用過的稀釋抗體。回收的抗體通常至少可以重復(fù)使用5-10次。稀釋后的抗體，包括已經(jīng)使用過的稀釋抗體，請4℃保存。
2. 回收后重復(fù)使用的抗體，使用方法同新鮮稀釋的抗體。如果在重復(fù)使用過程中發(fā)現(xiàn)抗體出現(xiàn)輕微混濁現(xiàn)象，可以10,000g離心1-3分鐘，取上清用于后續(xù)檢測。如果回收的抗體出現(xiàn)明顯的絮狀物或長霉長菌等情況，則可以考慮廢棄該抗體。
3. 提供的Western一抗稀釋液也可以用于免疫熒光(IF)、免疫組化(IHC)、免疫細胞化學(ICC)等適當用途。如果希望獲得zuì佳的檢測效果，請考慮使用上述檢測專用的一抗稀釋液。

儲存條件：-20℃，有效期一年。

根據(jù)您的關(guān)注的兔抗HER2/ErbB2抗體，兔抗HER2/ErbB2抗體，YT723，百奧萊博，，，您可能還對以下產(chǎn)品有需求：



名稱：小鼠抗Ku70抗體
貨號：YT735
規(guī)格：50μl
本品為來源于小鼠的抗Ku70的單克隆抗體。
宿主：小鼠
克隆性：單克隆抗體
用途：WB,IHC
交叉反應(yīng)性：人，小鼠
分子量：70KDa
推薦稀釋比例：WB(1:1000),IHC(1:50-1:100)

about this Antibody
Name	Ku70 Mouse Monoclonal Antibody
Category	Monoclonal antibody(mAb); Primary antibody
Isotype	IgG2a
Purification	ProA affinity purified
about the Immunogen
Immunogen	This antibody is produced by immunizing mice with a recombinant protein corresponding to a region of Ku70.
Gene ID	2547
SwissProt	P12956
Synonyms	70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; ATP-dependent DNA helicase II, 70 kDa subunit; CTC box binding factor 75 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF
Category	Cell Cycle / Checkpoint Control
Background	Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system.In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein.

注意事項：
1. 如果本抗體用于Western blot (WB)、免疫熒光(IF)、免疫細胞化學(ICC)等實驗，請注意回收使用過的稀釋抗體?；厥盏目贵w通常至少可以重復(fù)使用5-10次。稀釋后的抗體，包括已經(jīng)使用過的稀釋抗體，請4℃保存。
2. 回收后重復(fù)使用的抗體，使用方法同新鮮稀釋的抗體。如果在重復(fù)使用過程中發(fā)現(xiàn)抗體出現(xiàn)輕微混濁現(xiàn)象，可以10,000g離心1-3分鐘，取上清用于后續(xù)檢測。如果回收的抗體出現(xiàn)明顯的絮狀物或長霉長菌等情況，則可以考慮廢棄該抗體。
3. 提供的Western一抗稀釋液也可以用于免疫熒光(IF)、免疫組化(IHC)、免疫細胞化學(ICC)等適當用途。如果希望獲得zuì佳的檢測效果，請考慮使用上述檢測專用的一抗稀釋液。

儲存條件：-20℃，有效期一年。

關(guān)注兔抗HER2/ErbB2抗體，兔抗HER2/ErbB2抗體，YT723，百奧萊博，，的同時，為您推薦更多您可能感興趣的產(chǎn)品：

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