產品簡介
"上海博耀生物銷售Alpha-Fodrin Antibody #2122，CST原裝品質，價格優惠，訂購Alpha-Fodrin Antibody #2122，詳情請咨詢銷售人員
產品說明
"上海博耀生物銷售
Alpha-Fodrin Antibody #2122，CST原裝品質，價格優惠，訂購
Alpha-Fodrin Antibody #2122，詳情請咨詢銷售人員！
產品詳細參數如下>>>>
產品名稱：Alpha-Fodrin Antibody #2122
貨號：2122
品牌：CST(cell signaling)
抗體來源：Rabbit
克隆類型：
Polyclonal
規格：
| No. |
Size |
Price |
| 2122S |
100 ul (10 western blots) |
詢價 |
抗體應用：
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
H |
Endogenous |
150, 240 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度：
Alpha-Fodrin Antibody detects endogenous levels of full length alpha-fodrin (240 kDa) and its large fragment (150 kDa) resulting from cleavage at aspartic acid 1185.
來源及純化方法：
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp1185 of human alpha-fodrin. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景：
Fodrin (also named nonerythroid spectrin) is a universally expressed membrane-associated cytoskeletal protein consisting of alpha- and beta-subunits (1). This protein is important for maintaining normal membrane structure and supporting cell surface protein function (1). Alpha-fodrin is one of the primary targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases to yield amino-terminal 150 kDa, carboxy-terminal 120 kDa and 35 kDa major products (2-5). Cleavage of alpha-fodrin leads to membrane malfunction and cell shrinkage.
關鍵詞：CST，抗體，一抗{byao_back}{byao_back2}
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