產品簡介
"上海博耀生物銷售RhoA (67B9) Rabbit mAb #2117,CST原裝品質,價格優惠,訂購RhoA (67B9) Rabbit mAb #2117,詳情請咨詢銷售人
產品說明
"上海博耀生物銷售
RhoA (67B9) Rabbit mAb #2117,CST原裝品質,價格優惠,訂購
RhoA (67B9) Rabbit mAb #2117,詳情請咨詢銷售人員!
產品詳細參數如下>>>>
產品名稱:RhoA (67B9) Rabbit mAb #2117
貨號:2117
品牌:CST(cell signaling)
抗體來源:Rabbit
克隆類型:
Monoclonal
規格:
| No. |
Size |
Price |
| 2117P |
40 ul (4 western blots) |
詢價 |
| 2117S |
100 ul (10 western blots) |
詢價 |
抗體應用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Isotype |
| W |
H M R Mk B |
Endogenous |
21 |
Rabbit IgG |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Mk=Mon
key
B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度:
RhoA (67B9) Rabbit mAb recognizes endogenous levels of total RhoA protein. The antibody does not recognize the related proteins RhoB or RhoC.
來源及純化方法:
Monoclonal antibody is produced by immunizing animals with synthetic peptides corresponding to residues near the carboxy terminus of human RhoA.
抗體背景:
Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor (RhoGDI) (1). RhoA, RhoB and RhoC are highly homologous, but appear to have divergent biological functions. Carboxy-terminal modifications and differences in subcellular localization allow these three proteins to respond to and act on distinct signaling molecules (2,3).
關鍵詞:CST,抗體,一抗{byao_back}{byao_back2}
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