產品簡介
"上海博耀生物銷售Cleaved Lamin A (Asp230) Antibody #2031，CST原裝品質，價格優惠，訂購Cleaved Lamin A (Asp230) Antibody #
產品說明
"上海博耀生物銷售
Cleaved Lamin A (Asp230) Antibody #2031，CST原裝品質，價格優惠，訂購
Cleaved Lamin A (Asp230) Antibody #2031，詳情請咨詢銷售人員！
產品詳細參數如下>>>>
產品名稱：Cleaved Lamin A (Asp230) Antibody #2031
貨號：2031
品牌：CST(cell signaling)
抗體來源：Rabbit
克隆類型：
Polyclonal
規格：
| No. |
Size |
Price |
| 2031S |
100 ul (10 western blots) |
詢價 |
抗體應用：
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
H M R |
Endogenous |
45, 50 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度：
Cleaved Lamin A (Asp230) Antibody detects endogenous levels of the large fragment of lamin A (and lamin C isotype) resulting from cleavage at aspartic acid 230. The antibody does not recognize full length lamin A.
來源及純化方法：
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to carboxy-terminal residues surrounding Asp230 in human lamin A. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景：
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6).
關鍵詞：CST，抗體，一抗{byao_back}{byao_back2}
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免責聲明：以上所展示的[2031 Cleaved Lamin A (Asp230) Antibody #2031]信息由會員[]自行提供，內容的真實性、準確性和合法性由發布會員負責。
