產品簡介
"上海博耀生物銷售MEP50 (D56B8) Rabbit mAb #2018，CST原裝品質，價格優惠，訂購MEP50 (D56B8) Rabbit mAb #2018，詳情請咨詢銷
產品說明
"上海博耀生物銷售
MEP50 (D56B8) Rabbit mAb #2018，CST原裝品質，價格優惠，訂購
MEP50 (D56B8) Rabbit mAb #2018，詳情請咨詢銷售人員！
產品詳細參數如下>>>>
產品名稱：MEP50 (D56B8) Rabbit mAb #2018
貨號：2018
品牌：CST(cell signaling)
抗體來源：Rabbit
克隆類型：
Monoclonal
規格：
| No. |
Size |
Price |
| 2018S |
100 ul (10 western blots) |
詢價 |
抗體應用：
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Isotype |
| W IP |
H M R Mk |
Endogenous |
42 |
Rabbit IgG |
Applications Key:
W=Western Blotting
IP=Immunoprecipitation
Reactivity Key:
H=Human
M=Mouse
R=Rat
Mk=Mon
key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度：
MEP50 (D56B8) Rabbit mAb detects endogenous levels of MEP50 protein.
來源及純化方法：
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to amino acids surrounding Ser225 of human MEP50.
抗體背景：
MEP50 (methylosome protein 50) is a component of the methylosome, a protein arginine methyltransferase complex that modifies specific arginine residues found in arginine- and glycine-rich regions of some spliceosomal Sm proteins. MEP50 is important for methylosome activity and may regulate the transfer of Sm proteins to the SMN (survival of motor neurons) complex, an early step in the assembly of U snRNPs. Both the methylosome and the SMN complex are essential for the assembly of spliceosomal snRNPs (1).MEP50 is a WD repeat protein that may provide an interface for multiple protein interactions between methylosome proteins. (1). It binds to JBP1, an arginine protein methyltransferase component of the methylosome. MEP50 has been shown to interact with CTD phosphatase FCP1 (CTDP1), a protein that may link the processes of transcriptional elongation and splicing (2), and with SUZ12, a polycomb group protein involved in transcriptional repression (3). JBP1 and MEP50 have also been reported to interact with the methyl-CpG binding protein complex MBD2/NuRD (4).
關鍵詞：CST，抗體，一抗{byao_back}{byao_back2}
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免責聲明：以上所展示的[2018 MEP50 (D56B8) Rabbit mAb #2018]信息由會員[]自行提供，內容的真實性、準確性和合法性由發布會員負責。
