產品簡介
"上海博耀生物銷售Phospho-β-Catenin (Ser33/37) Antibody #2009，CST原裝品質，價格優惠，訂購Phospho-β-Catenin (Ser33/37)
產品說明
"上海博耀生物銷售
Phospho-β-Catenin (Ser33/37) Antibody #2009，CST原裝品質，價格優惠，訂購
Phospho-β-Catenin (Ser33/37) Antibody #2009，詳情請咨詢銷售人員！
產品詳細參數如下>>>>
產品名稱：Phospho-β-Catenin (Ser33/37) Antibody #2009
貨號：2009
品牌：CST(cell signaling)
抗體來源：Rabbit
克隆類型：
Polyclonal
規格：
| No. |
Size |
Price |
| 2009S |
100 ul (10 western blots) |
詢價 |
抗體應用：
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W IP |
H (M) (R) (X) (Z) |
Endogenous |
92 |
Rabbit |
Applications Key:
W=Western Blotting
IP=Immunoprecipitation
Reactivity Key:
H=Human
M=Mouse
R=Rat
X=Xenopus
Z=Zebrafish
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度：
Phospho-β-Catenin (Ser33/37) Antibody detects endogenous levels of β-catenin only when phosphorylated at Ser33 and Ser37.
來源及純化方法：
Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser33 and Ser37 of human β-catenin. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景：
β-Catenin is a key downstream effector in the Wnt signaling pathway (1). It is implicated in two major biological processes in vertebrates: early embryonic development (2) and tumorigenesis (3). CK1 phosphorylates β-catenin at Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3β (4-6). GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41 (7). Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines (8).
關鍵詞：CST，抗體，一抗{byao_back}{byao_back2}
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